Microarray technology slides, HTML, PDF, Rmd

References

  • Tumor Analysis Best Practices Working Group. “Expression Profiling–Best Practices for Data Generation and Interpretation in Clinical Trials.” Nature Reviews. Genetics 5, no. 3 (March 2004): 229–37. doi:10.1038/nrg1297. https://www.ncbi.nlm.nih.gov/pubmed/14970825 - Microarray overview. Best practices for technology and analysis.

  • Lipshutz, R. J., S. P. Fodor, T. R. Gingeras, and D. J. Lockhart. “High Density Synthetic Oligonucleotide Arrays.” Nature Genetics 21, no. 1 Suppl (January 1999): 20–24. doi:10.1038/4447. https://www.ncbi.nlm.nih.gov/pubmed/15737073 - Description of Affymetrix technology

Videos

http://www.bio.davidson.edu/courses/genomics/chip/chip.html

  • demo of how microarrays work

https://youtu.be/MRmpeBTwwWw - photolitographic manufacturing of oligonucleotide arrays