Course logistics

Instructor: Mikhail G. Dozmorov mikhail.dozmorov@vcuhealth.org, Ph.D.; Jin Liu (TA)

Schedule: Monday, Wednesday 1:00pm – 2:20pm

Classroom: One Capital Square (OCS) 5009

Office hours: Mon, Wed 2:30pm – 4:00pm, OCS 730; TA: Mon, Wed 10:30am - 12:00pm

Course documents: https://blackboard.vcu.edu, https://mdozmorov.github.io/BIOS567/

Course prerequisites

Prerequisites: BIOS 524 Biostatistical Computing, BIOS 553 Linear Regression, and BIOS 554 ANOVA

Required text: Sorin Draghici “Statistics and Data Analysis for Microarrays Using R and Bioconductor”, 2nd Ed., Chapman & Hall/CRC Press, 2012. ISBN-978-1-4398-0975-4, Supplemental course materials provided in-class

Software: The R programming environment

Computational Genomics

Genomics/Bioinformatics (general)

• Generation, organization, and analysis of biological data (initially genomic data)

Biostatistics

• Class of statistical methods for dealing with large biological data sets
• Goal: statistically identify significant changes in biological processes to answer relevant biological questions.
• High-throughput studies; get data matrix; mine the matrix for information

Microarrays

Counts of papers per year in PubMed having microarray word